Preliminary program - LRUA 2022
Day 1 (October 31, 2022) – Uppsala University Main Building
08:30 – 10:30 Registration and coffee
*** LONG-READ SEQUENCING UPDATES
10:30 - 10:35 Welcome to LRUA22, Olga Vinnere Pettersson
10:35 - 10:50 Long-read sequencing at SciLifeLab NGI, Adam Ameur
10:50 - 11:15 Updates from ONT, Tonya McSherry, Global Director New Markets
11:15 - 11:40 Updates from PacBio, Jonas Korlach, Chief Scientific Officer
*** BIODIVERSITY
11:40 - 12:10 TBA, Mark Blaxter, Wellcome Sanger Institute, UK
12:10 - 13:30 Lunch & posters
*** BIODIVERSITY Cont.
13:30 - 13:50 Genomic analyses of the Linum distyly supergene reveal convergent
evolution at the molecular level, Tanja Slotte, Stockholm university, Sweden
13:50 - 14:10 TBA, Camila Mazzoni, IZW, Berlin, Germany
14:10 - 14:30 Chromosome-scale assemblies of Norway spruce and Scots pine, Nathaniel
Street, Umeå Plant Science Centre, Umeå University, Sweden
14:30 - 14:50 TBA, Valentina Peona, Uppsala university, Sweden
14:50 - 15:00 Silver sponsor
15:00 - 15:40 Coffee & posters
*** WHAT’S NEXT IN LONG-READ SEQUENCING?
15:40 - 16:10 Streamlining clinical genetic testing: the promise of long-read sequencing, Danny Miller, University of Washington, USA
16:10 - 16:30 Single-cell Analysis of Alternative Splicing in Hematopoietic Stem and Progenitor Cells, Laura Mincarelli, CRUK Beatson Institute, UK
16:30 - 16:50 Single-cell transcript isoform sequencing of the activated adult mouse hippocampus, Sheridan Cavalier, Johns Hopkins School of Medicine, USA
16:50 - 17:10 Long-read sequencing techniques in study of somatic transposition in the Drosophila intestine, Natalia Rubanova, Institut Curie, Paris, France
18.30 – Late Conference dinner (Norrlands Nation)
https://www.lrua2022.se/
Day 2 (November 1, 2022) – Uppsala University Main Building
*** TECHNOLOGY & APPLICATIONS - COMPUTATIONAL APPROACHES
09:00 - 09:30 TBA, Ana Conesa, National Research Council, Spain
09:30 - 09:50 Advanced approaches for chromosome-scale haplotype-resolved assembly and pangenomics, Shilpa Garg, University of Copenhagen, Denmark
09:50 - 10:10 Verkko: telomere-to-telomere assembly of diploid chromosomes, Mikko
Rautiainen, National Institutes of Health USA & FIMM Finland
10:10 - 10:20 Silver sponsor
10:20 - 11:00 Coffee & posters
*** HUMAN/MEDICAL SEQUENCING
11:00 - 11:30 Recent progress in human genome analysis using Nanopore long reads, Miten Jain, Northeastern University, Boston, USA
11:30 - 11:50 Comprehensive human brain transcriptome characterisation using long-read Capture Sequencing, Sofia Kudasheva, UK
11:50 - 12:10 Quantifying Genome-Editing Outcomes Using Long-Read Sequencing and Beyond, Ayal Hendel, Bar-Ilan University, Israel
12:10 - 12:20 Silver sponsor
12:20 - 13:30 Lunch & posters
*** HUMAN/MEDICAL SEQUENCING Cont.
13:30 - 14:00 Long-read genomics for rare diseases, Alexander Hoischen, Radboud University Medical Center, Nijmegen, The Netherlands
14:00 - 14:20 Application of nanopore sequencing for liquid biopsy analysis, Carolin Sauer, EMBL-EBI, UK
14:20 - 14:40 Transcriptome variation in human tissues uncovered by long-read
sequencing, Tuuli Lappalainen, SciLifelab/KTH Sweden & New York Genome Center USA
14:40 - 15:00 Long-read sequencing reveals novel transcripts induced by misexpression of
DUX4 in FSHD muscle, Dongxu Zheng, The Netherlands
15:00 - 15:10 Silver sponsor
15:10 - 15:50 Coffee & posters
*** TECHNOLOGY & APPLICATIONS - CHALLENGES
15:50 - 16:10 TBA, Melissa Laird Smith, University of Louisville, USA
16:10 - 16:30 TBA, Andreas Wallberg, Uppsala university, Sweden
16:30 - 16:50 Long-read sequencing assay allows accurate characterization of the HIV-1
reservoir, Laurens Lambrechts, Ghent University, Belgium
16:50 - 17:10 TBA, Maliheh Mershad, SLU, Sweden
17:10 - 17:30 Genomic signatures of single Platynothrus peltifer from chromosome-scale
genome assembly with resolved haplotypes, Shan Gao, University of Cologne, Germany
Day 3 (November 3, 2022) – Uppsala University Main Building
09:00 - 10:30 Workshop - Oxford Nanopore Technologies
10:30 - 11:00 Coffee
11:00 - 12:30 Workshop - PacBio
12:30 - 13:30 Lunch (on your own)
13.30 - 16.00 Satellite meetings and workshops:
• Bioinformatics for biodiversity genomics (open meeting)
Kerstin Howe, Sanger, UK
Tyler Alioto, CNAG, Barcelona, Spain
Henrik Lantz, NBIS, Sweden
Discussions
• Clinical long-read sequencing in Sweden (closed meeting)
• Facility forum organized by the BGE consortium (closed meeting)